Pralidoxime chloride IP

Pralidoxime chloride IP

2-Pyridine aldoxime methyl chloride;Pralidoxime chloride;1-Methyl-2-pyridinium-3-aldoxime chloride

CAS 51-15-0

Chemical Formula C9H11ClN2O

Molecular Weight 196.65 g/mol

Pralidoxime chloride IP (Indian Pharmacopoeia) is a medication used primarily as an antidote to treat poisoning caused by organophosphates, such as those found in certain insecticides and nerve agents. It works by reactivating acetylcholinesterase, an enzyme inhibited by organophosphates, thereby helping to restore normal nerve function. Pralidoxime chloride is commonly administered in conjunction with atropine, another antidote, to counteract the effects of poisoning. It is typically used in emergency medical settings to manage severe toxicity symptoms.

Industrial Uses

1. Pharmaceuticals

  • Antidote for Organophosphate Poisoning: Pralidoxime chloride is primarily used in emergency medicine as an antidote to treat organophosphate poisoning. It works by reactivating acetylcholinesterase, an enzyme inhibited by organophosphates, thus reversing the toxic effects and restoring normal nerve function.
  • Adjunct to Atropine in Poisoning: It is often used in combination with atropine to treat poisoning from nerve agents or certain insecticides. While atropine addresses the symptoms by blocking acetylcholine receptors, pralidoxime chloride helps to regenerate the acetylcholinesterase enzyme.
  • Toxicology Research: Used in clinical toxicology research and as a part of antidotal therapy in laboratories and medical settings to study the effects of neurotoxic substances.

2. Chemical Synthesis

  • Intermediate in Drug Synthesis: Pralidoxime chloride can be used as a precursor or intermediate in the synthesis of other oxime derivatives used for chemical defense or as therapeutic agents against different types of poisoning.
  • Development of New Antidotes: The compound's reactivation properties can be explored for the development of other chemical antidotes, making it a valuable tool in chemical synthesis for pharmaceutical applications.

3. Agrochemicals

  • Antidote for Pesticide Poisoning: Pralidoxime chloride can be applied in agriculture for pesticide poisoning cases, particularly where exposure to organophosphates occurs, helping to treat workers or individuals who have been affected by chemical pesticides.
  • Agricultural Safety: In farming communities, pralidoxime chloride may be used to counteract exposure to organophosphate-based insecticides, enhancing safety standards and reducing the risk of poisoning in workers.

4. Animal Healthcare

  • Treatment for Animal Poisoning: It is also used in veterinary medicine for the treatment of poisoning in animals, especially those that have been exposed to organophosphate insecticides. It helps restore normal neurological function in affected animals.
  • Livestock Safety: Pralidoxime chloride may be applied in cases of toxicological emergencies involving livestock or pets, particularly in agricultural settings where animals are at risk of pesticide exposure.

Specifications

Solubility Soluble in water
Density 1.18 g/cm³
Flash Point Not applicable (solid)
Appearance White to off-white crystalline powder
Assay ≥99%
Melting Point 150-153°C
Odor Odorless
Boiling Point 365°C (at 760 mmHg)
Viscosity Not available

Hazard Symbols

Acute Toxicity
Irritants/Sensitisers/Other Hazards
Environmental Hazard

FAQs

1. What is the current price of Pralidoxime chloride IP in India?
The price of Pralidoxime chloride IP can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91-6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Pralidoxime chloride IP in India?
You can purchase Pralidoxime chloride IP from MULTICHEM, a leading importer with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across India. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Pralidoxime chloride IP?
Our minimum order quantity (MOQ) for Pralidoxime chloride IP is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Pralidoxime chloride IP supplied by Multichem ?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.